A revised model of TRAIL‐R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis

The long FLIP splice form FLIP(L) can act as both an inhibitor and promoter of caspase‐8 at death‐inducing signalling complexes (DISCs) formed by death receptors such as TRAIL‐R2 and related intracellular complexes such as the ripoptosome. Herein, we describe a revised DISC assembly model that expla...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Humphreys, Luke M, Fox, Jennifer P, Higgins, Catherine A, Majkut, Joanna, Sessler, Tamas, McLaughlin, Kirsty, McCann, Christopher, Roberts, Jamie Z, Crawford, Nyree T, McDade, Simon S, Scott, Christopher J, Harrison, Timothy, Longley, Daniel B
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054686/
https://ncbi.nlm.nih.gov/pubmed/32009295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949254
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados