Design, Synthesis and Structure-Activity Relationships of 4-Phenyl-1H-1,2,3-Triazole Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Promising Antiviral Activities

HIV-1 CA is involved in different stages of the viral replication cycle, performing essential roles in both early (uncoating, reverse transcription, nuclear import, integration) and late events (assembly). Recent efforts have demonstrated HIV-1 CA protein as a prospective therapeutic target for the...

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Vydáno v:Eur J Med Chem
Hlavní autoři: Sun, Lin, Huang, Tianguang, Dick, Alexej, Meuser, Megan E., Zalloum, Waleed A., Chen, Chin Ho, Ding, Xiao, Gao, Ping, Cocklin, Simon, Lee, Kuo-Hsiung, Zhan, Peng, Liu, Xinyong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053825/
https://ncbi.nlm.nih.gov/pubmed/32066010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112085
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