Discovery of Phenylalanine Derivatives as Potent HIV-1 Capsid Inhibitors from Click Chemistry-based Compound Library

The HIV-1 capsid (CA) protein plays essential roles in both early and late stages of HIV-1 replication and is considered an important, clinically unexploited therapeutic target. As such, small drug-like molecules that inhibit this critical HIV-1 protein have become a priority for several groups. The...

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Publicado no:Eur J Med Chem
Main Authors: Wu, Gaochan, Zalloum, Waleed A., Meuser, Megan E., Jing, Lanlan, Kang, Dongwei, Chen, Chin Ho, Tian, Ye, Zhang, Fangfang, Cocklin, Simon, Lee, Kuo-Hsiung, Liu, Xinyong, Zhan, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550353/
https://ncbi.nlm.nih.gov/pubmed/30243152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.09.029
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