Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors

The HIV-1 capsid (CA) protein plays crucial roles in both early and late stages of the viral life cycle, which has intrigued researchers to target it to develop anti-HIV drugs. Accordingly, in this research, we report the design, synthesis and biological evaluation of a series of novel phenylalanine...

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Detalhes bibliográficos
Publicado no:RSC Adv
Main Authors: Jiang, Xiangyi, Wu, Gaochan, Zalloum, Waleed A., Meuser, Megan E., Dick, Alexej, Sun, Lin, Chen, Chin-Ho, Kang, Dongwei, Jing, Lanlan, Jia, Ruifang, Cocklin, Simon, Lee, Kuo-Hsiung, Liu, Xinyong, Zhan, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2019
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034945/
https://ncbi.nlm.nih.gov/pubmed/32089839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ra05869a
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