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Bayesian Framework for Detecting Gene Expression Outliers in Individual Samples

PURPOSE: Many antineoplastics are designed to target upregulated genes, but quantifying upregulation in a single patient sample requires an appropriate set of samples for comparison. In cancer, the most natural comparison set is unaffected samples from the matching tissue, but there are often too fe...

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Detalhes bibliográficos
Publicado no:JCO Clin Cancer Inform
Main Authors: Vivian, John, Eizenga, Jordan M., Beale, Holly C., Vaske, Olena M., Paten, Benedict
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053807/
https://ncbi.nlm.nih.gov/pubmed/32097024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.19.00095
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