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Bayesian Framework for Detecting Gene Expression Outliers in Individual Samples

PURPOSE: Many antineoplastics are designed to target upregulated genes, but quantifying upregulation in a single patient sample requires an appropriate set of samples for comparison. In cancer, the most natural comparison set is unaffected samples from the matching tissue, but there are often too fe...

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Detalles Bibliográficos
Publicado en:JCO Clin Cancer Inform
Main Authors: Vivian, John, Eizenga, Jordan M., Beale, Holly C., Vaske, Olena M., Paten, Benedict
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Clinical Oncology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053807/
https://ncbi.nlm.nih.gov/pubmed/32097024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.19.00095
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