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Bayesian Framework for Detecting Gene Expression Outliers in Individual Samples

PURPOSE: Many antineoplastics are designed to target upregulated genes, but quantifying upregulation in a single patient sample requires an appropriate set of samples for comparison. In cancer, the most natural comparison set is unaffected samples from the matching tissue, but there are often too fe...

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Bibliographische Detailangaben
Veröffentlicht in:JCO Clin Cancer Inform
Hauptverfasser: Vivian, John, Eizenga, Jordan M., Beale, Holly C., Vaske, Olena M., Paten, Benedict
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053807/
https://ncbi.nlm.nih.gov/pubmed/32097024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.19.00095
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