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Modelling haplotypes with respect to reference cohort variation graphs

MOTIVATION: Current statistical models of haplotypes are limited to panels of haplotypes whose genetic variation can be represented by arrays of values at linearly ordered bi- or multiallelic loci. These methods cannot model structural variants or variants that nest or overlap. RESULTS: A variation...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Rosen, Yohei, Eizenga, Jordan, Paten, Benedict
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870562/
https://ncbi.nlm.nih.gov/pubmed/28881971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx236
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