HopLand: single-cell pseudotime recovery using continuous Hopfield network-based modeling of Waddington’s epigenetic landscape

MOTIVATION: The interpretation of transcriptional dynamics in single-cell data, especially pseudotime estimation, could help understand the transition of gene expression profiles. The recovery of pseudotime increases the temporal resolution of single-cell transcriptional data, but is challenging due...

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Publicado en:Bioinformatics
Autores principales: Guo, Jing, Zheng, Jie
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
Materias:
Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870541/
https://ncbi.nlm.nih.gov/pubmed/28881967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx232
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