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Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway

It has been widely reported that advanced maternal age impairs oocyte quality. To date, various molecules have been discovered to be involved in this process. However, prevention of fertility issues associated with maternal age is still a challenge. In the present study, we find that both in vitro s...

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Bibliografski detalji
Izdano u:Aging (Albany NY)
Glavni autori: Li, Congyang, He, Xi, Huang, Zhenyue, Han, Longsen, Wu, Xinghan, Li, Ling, Xin, Yongan, Ge, Juan, Sha, Jiahao, Yin, Zhiqiang, Wang, Qiang
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053624/
https://ncbi.nlm.nih.gov/pubmed/31980591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102703
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