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SIRT6 participates in the quality control of aged oocytes via modulating telomere function

It has been well recognized that oocyte quality declines in aging animals. However, to date, the underlying mechanism remains to be explored. In the present study, we report that oocytes and embryos from aged mice (42-45 weeks old) display the reduced expression of SIRT6 protein, accompanying with t...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Ge, Juan, Li, Congyang, Li, Chunling, Huang, Zhenyue, Zeng, Juan, Han, Longsen, Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503879/
https://ncbi.nlm.nih.gov/pubmed/30926765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101885
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