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Involvement of SIRT3‐GSK3β deacetylation pathway in the effects of maternal diabetes on oocyte meiosis

OBJECTIVES: It has been widely reported that maternal diabetes impairs oocyte quality. However, the responsible mechanisms remain to be explored. In the present study, we focused on whether SIRT3‐GSK3β pathway mediates the meiotic defects in oocytes from diabetic mice. MATERIALS AND METHODS: GSK3β f...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Xin, Yongan, Jin, Yifei, Ge, Juan, Huang, Zhenyue, Han, Longsen, Li, Congyang, Wang, Danni, Zhu, Shuai, Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791178/
https://ncbi.nlm.nih.gov/pubmed/33107080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12940
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