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Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte
Sirt6, a member of the sirtuin family of NAD-dependent protein deacetylases, has been implicated in multiple biological processes. However, the roles of Sirt6 in meiosis have not been addressed. In the present study, by employing knockdown analysis in mouse oocytes, we evaluated the effects of Sirt6...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4612726/ https://ncbi.nlm.nih.gov/pubmed/26481302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15366 |
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