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Rab5a is required for spindle length control and kinetochore-microtubule attachment during meiosis in oocytes

Rab GTPases are highly conserved components of vesicle trafficking pathways. Rab5, as a master regulator of endocytic trafficking, has been shown to function in membrane tethering and docking. However, the function of Rab5 in meiosis has not been addressed. Here, we report elongated spindles and mis...

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Bibliographische Detailangaben
Veröffentlicht in:FASEB J
Hauptverfasser: Ma, Rujun, Hou, Xiaojing, Zhang, Liang, Sun, Shao-Chen, Schedl, Tim, Moley, Kelle, Wang, Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395731/
https://ncbi.nlm.nih.gov/pubmed/24876181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-250886
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