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Rab5a is required for spindle length control and kinetochore-microtubule attachment during meiosis in oocytes

Rab GTPases are highly conserved components of vesicle trafficking pathways. Rab5, as a master regulator of endocytic trafficking, has been shown to function in membrane tethering and docking. However, the function of Rab5 in meiosis has not been addressed. Here, we report elongated spindles and mis...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Ma, Rujun, Hou, Xiaojing, Zhang, Liang, Sun, Shao-Chen, Schedl, Tim, Moley, Kelle, Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395731/
https://ncbi.nlm.nih.gov/pubmed/24876181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-250886
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