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Zwint-1 is required for spindle assembly checkpoint function and kinetochore-microtubule attachment during oocyte meiosis

The key step for faithful chromosome segregation during meiosis is kinetochore assembly. Defects in this process result in aneuploidy, leading to miscarriages, infertility and various birth defects. However, the roles of kinetochores in homologous chromosome segregation during meiosis are ill-define...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Woo Seo, Dong, Yeop You, Seung, Chung, Woo-Jae, Cho, Dong-Hyung, Kim, Jae-Sung, Su Oh, Jeong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614028/
https://ncbi.nlm.nih.gov/pubmed/26486467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15431
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