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Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosis

Sirtuins have been widely reported to be involved in multiple biological processes; however, their function in oocyte meiosis has not been. Here, by confocal scanning and quantitative analysis, we show that specific depletion of Sirt2 in mouse oocytes results in spindle defects and chromosome disorg...

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Detalhes bibliográficos
Main Authors: Zhang, Liang, Hou, Xiaojing, Ma, Rujun, Moley, Kelle, Schedl, Tim, Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929683/
https://ncbi.nlm.nih.gov/pubmed/24334550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-244111
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