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Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosis

Sirtuins have been widely reported to be involved in multiple biological processes; however, their function in oocyte meiosis has not been. Here, by confocal scanning and quantitative analysis, we show that specific depletion of Sirt2 in mouse oocytes results in spindle defects and chromosome disorg...

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מידע ביבליוגרפי
Main Authors: Zhang, Liang, Hou, Xiaojing, Ma, Rujun, Moley, Kelle, Schedl, Tim, Wang, Qiang
פורמט: Artigo
שפה:Inglês
יצא לאור: Federation of American Societies for Experimental Biology 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929683/
https://ncbi.nlm.nih.gov/pubmed/24334550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-244111
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