Sirt3 prevents maternal obesity-associated oxidative stress and meiotic defects in mouse oocytes

Maternal obese environment has been reported to induce oxidative stress and meiotic defects in oocytes, however the underlying molecular mechanism remains unclear. Here, using mice fed a high fat diet (HFD) as an obesity model, we first detected enhanced reactive oxygen species (ROS) content and red...

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Dettagli Bibliografici
Pubblicato in:Cell Cycle
Autori principali: Zhang, Liang, Han, Longsen, Ma, Rujun, Hou, Xiaojing, Yu, Yang, Sun, Shaochen, Xu, Yinxue, Schedl, Tim, Moley, Kelle H, Wang, Qiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825572/
https://ncbi.nlm.nih.gov/pubmed/25790176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026517
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