Sirt3 prevents maternal obesity-associated oxidative stress and meiotic defects in mouse oocytes

Maternal obese environment has been reported to induce oxidative stress and meiotic defects in oocytes, however the underlying molecular mechanism remains unclear. Here, using mice fed a high fat diet (HFD) as an obesity model, we first detected enhanced reactive oxygen species (ROS) content and red...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Zhang, Liang, Han, Longsen, Ma, Rujun, Hou, Xiaojing, Yu, Yang, Sun, Shaochen, Xu, Yinxue, Schedl, Tim, Moley, Kelle H, Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825572/
https://ncbi.nlm.nih.gov/pubmed/25790176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026517
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