Sirt3 prevents maternal obesity-associated oxidative stress and meiotic defects in mouse oocytes

Maternal obese environment has been reported to induce oxidative stress and meiotic defects in oocytes, however the underlying molecular mechanism remains unclear. Here, using mice fed a high fat diet (HFD) as an obesity model, we first detected enhanced reactive oxygen species (ROS) content and red...

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Publicado en:Cell Cycle
Autores principales: Zhang, Liang, Han, Longsen, Ma, Rujun, Hou, Xiaojing, Yu, Yang, Sun, Shaochen, Xu, Yinxue, Schedl, Tim, Moley, Kelle H, Wang, Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825572/
https://ncbi.nlm.nih.gov/pubmed/25790176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1026517
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