Chromosome misalignments induce spindle‐positioning defects

Cortical pulling forces on astral microtubules are essential to position the spindle. These forces are generated by cortical dynein, a minus‐end directed motor. Previously, another dynein regulator termed Spindly was proposed to regulate dynein‐dependent spindle positioning. However, the mechanism o...

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Bibliographic Details
Published in:EMBO Rep
Main Authors: Tame, Mihoko A, Raaijmakers, Jonne A, Afanasyev, Pavel, Medema, René H
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772978/
https://ncbi.nlm.nih.gov/pubmed/26882550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541143
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