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Chromosomes trapped in micronuclei are liable to segregation errors

DNA in micronuclei is likely to get damaged. When shattered DNA from micronuclei gets reincorporated into the primary nucleus, aberrant rearrangements can take place, a phenomenon referred to as chromothripsis. Here, we investigated how chromatids from micronuclei act in subsequent divisions and how...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Soto, Mar, García-Santisteban, Iraia, Krenning, Lenno, Medema, René H., Raaijmakers, Jonne A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051344/
https://ncbi.nlm.nih.gov/pubmed/29930083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.214742
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