Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway

It has been widely reported that advanced maternal age impairs oocyte quality. To date, various molecules have been discovered to be involved in this process. However, prevention of fertility issues associated with maternal age is still a challenge. In the present study, we find that both in vitro s...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Li, Congyang, He, Xi, Huang, Zhenyue, Han, Longsen, Wu, Xinghan, Li, Ling, Xin, Yongan, Ge, Juan, Sha, Jiahao, Yin, Zhiqiang, Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053624/
https://ncbi.nlm.nih.gov/pubmed/31980591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102703
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