SIRT4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

SIRT4 modulates energy homeostasis in multiple cell types and tissues. However, its role in meiotic oocytes remains unknown. Here, we report that mouse oocytes overexpressing SIRT4 are unable to completely progress through meiosis, showing the inadequate mitochondrial redistribution, lowered ATP con...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Zeng, Juan, Jiang, Manxi, Wu, Xinghan, Diao, Feiyang, Qiu, Danhong, Hou, Xiaojing, Wang, Haichao, Li, Ling, Li, Chunling, Ge, Juan, Liu, Jiayin, Ou, Xianghong, Wang, Qiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052465/
https://ncbi.nlm.nih.gov/pubmed/29845740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12789
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