SIRT4 is essential for metabolic control and meiotic structure during mouse oocyte maturation

SIRT4 modulates energy homeostasis in multiple cell types and tissues. However, its role in meiotic oocytes remains unknown. Here, we report that mouse oocytes overexpressing SIRT4 are unable to completely progress through meiosis, showing the inadequate mitochondrial redistribution, lowered ATP con...

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Detalles Bibliográficos
Publicado en:Aging Cell
Main Authors: Zeng, Juan, Jiang, Manxi, Wu, Xinghan, Diao, Feiyang, Qiu, Danhong, Hou, Xiaojing, Wang, Haichao, Li, Ling, Li, Chunling, Ge, Juan, Liu, Jiayin, Ou, Xianghong, Wang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052465/
https://ncbi.nlm.nih.gov/pubmed/29845740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12789
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