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Rab6a is a novel regulator of meiotic apparatus and maturational progression in mouse oocytes

Rab family GTPases have been well known to regulate intracellular vesicle transport, however their function in mammalian oocytes has not been addressed. In this study, we report that when Rab6a is specifically knockdown, mouse oocytes are unable to progress normally through meiosis, arresting at met...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Hou, Xiaojing, Zhang, Jiaqi, Li, Ling, Ma, Rujun, Ge, Juan, Han, Longsen, Wang, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768169/
https://ncbi.nlm.nih.gov/pubmed/26915694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22209
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