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Rab6a is a novel regulator of meiotic apparatus and maturational progression in mouse oocytes
Rab family GTPases have been well known to regulate intracellular vesicle transport, however their function in mammalian oocytes has not been addressed. In this study, we report that when Rab6a is specifically knockdown, mouse oocytes are unable to progress normally through meiosis, arresting at met...
Gespeichert in:
| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768169/ https://ncbi.nlm.nih.gov/pubmed/26915694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22209 |
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