Mitofusin1 in oocyte is essential for female fertility

Mitofusins (Mfn) are the important regulators of mitochondrial organization in mammalian cells; however, their roles during oocyte development remain unknown. In the present study, we generated mice with oocyte-specific knockout of Mfn1 or Mfn2 (Mfn1(fl/fl);Zp3-Cre or Mfn2(fl/fl);Zp3-Cre). We report...

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Vydáno v:Redox Biol
Hlavní autoři: Hou, Xiaojing, Zhu, Shuai, Zhang, Hao, Li, Chunling, Qiu, Danhong, Ge, Juan, Guo, Xuejiang, Wang, Qiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351231/
https://ncbi.nlm.nih.gov/pubmed/30690319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101110
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