MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) localized protein that regulates ER homeostasis and unfolded protein response (UPR). The biology of endogenous MANF in the mammalian brain is unknown and therefore we studied the brain phenotype of MANF-defic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eNeuro
Egile Nagusiak: Pakarinen, Emmi, Danilova, Tatiana, Võikar, Vootele, Chmielarz, Piotr, Piepponen, Petteri, Airavaara, Mikko, Saarma, Mart, Lindahl, Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2020
Gaiak:
Research Article: New Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053174/
https://ncbi.nlm.nih.gov/pubmed/32005751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0477-19.2019
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak