Cyclophosphamide-induced cystitis results in NLRP3-mediated inflammation in the hippocampus and symptoms of depression in rats

Recent breakthroughs demonstrate that peripheral diseases can trigger inflammation in the brain, causing psychosocial maladies, including depression. While few direct studies have been made, anecdotal reports associate urological disorders with mental dysfunction. Thus, we investigated if insults ta...

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Detalles Bibliográficos
Publicado en:Am J Physiol Renal Physiol
Main Authors: Hirshman, Nathan A., Hughes, Francis M., Jin, Huixia, Harrison, William T., White, Simon W., Doan, Isabelle, Harper, Shelby N., Leidig, Patrick D., Purves, J. Todd
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052649/
https://ncbi.nlm.nih.gov/pubmed/31869244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00408.2019
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