Cyclophosphamide-induced cystitis results in NLRP3-mediated inflammation in the hippocampus and symptoms of depression in rats

Recent breakthroughs demonstrate that peripheral diseases can trigger inflammation in the brain, causing psychosocial maladies, including depression. While few direct studies have been made, anecdotal reports associate urological disorders with mental dysfunction. Thus, we investigated if insults ta...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Hirshman, Nathan A., Hughes, Francis M., Jin, Huixia, Harrison, William T., White, Simon W., Doan, Isabelle, Harper, Shelby N., Leidig, Patrick D., Purves, J. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052649/
https://ncbi.nlm.nih.gov/pubmed/31869244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00408.2019
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