The NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3) Inflammasome Mediates Inflammation and Voiding Dysfunction in a Lipopolysaccharide-Induced Rat Model of Cystitis

OBJECTIVE: NOD-like receptors (NLRs) sense sterile and non-sterile signals and form inflammasomes which trigger an inflammatory response through the activation of caspase-1 and release of IL-1β. Recently we have shown the presence of several NLRs in the bladder urothelia and demonstrated the importa...

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Detalhes bibliográficos
Publicado no:J Clin Cell Immunol
Main Authors: Hughes, Francis M, Kennis, James G, Youssef, Melissa N, Lowe, Danielle W, Shaner, Brooke E, Purves, J Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825681/
https://ncbi.nlm.nih.gov/pubmed/27066297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000396
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