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Calcium Pyrophosphate And Monosodium Urate Activate The NLRP3 Inflammasome Within Bladder Urothelium Via Reactive Oxygen Species And TXNIP

OBJECTIVE: To investigate the in vitro activation of the NLRP3 inflammasome within bladder urothelium by stone-forming components. Further, to describe the contributions of reactive oxygen species (ROS) and thioredoxin-interacting protein (TXNIP), an important structural component of the inflammasom...

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Detalhes bibliográficos
Publicado no:Res Rep Urol
Main Authors: Harper, Shelby N, Leidig, Patrick D, Hughes, Francis M, Jin, Huixia, Purves, J Todd
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879004/
https://ncbi.nlm.nih.gov/pubmed/31819864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/RRU.S225767
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