NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation

The NLRP3 inflammasome senses diabetic metabolites and initiates inflammation implicated in diabetic complications and neurodegeneration. No studies have investigated NLRP3 in diabetic bladder dysfunction (DBD), despite a high clinical prevalence. In vitro, we found that numerous diabetic metabolite...

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Vydáno v:Diabetes
Hlavní autoři: Hughes, Francis M., Hirshman, Nathan A., Inouye, Brian M., Jin, Huixia, Stanton, Eloise W., Yun, Chloe E., Davis, Leah G., Routh, Jonathan C., Purves, J. Todd
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2019
Témata:
Complications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341307/
https://ncbi.nlm.nih.gov/pubmed/30425063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0845
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