A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

Neurofibrillary tangles are a pathological hallmark of Alzheimer’s disease, and their levels correlate with the severity of cognitive dysfunction in humans. However, experimental evidence suggests that soluble tau species cause cognitive deficits and memory impairment. Our recent study suggests that...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Liu, Peng, Smith, Benjamin R., Montonye, Michelle L., Kemper, Lisa J., Leinonen-Wright, Kailee, Nelson, Kathryn M., Higgins, LeeAnn, Guerrero, Candace R., Markowski, Todd W., Zhao, Xiaohui, Petersen, Ashley J., Knopman, David S., Petersen, Ronald C., Ashe, Karen H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052165/
https://ncbi.nlm.nih.gov/pubmed/32123248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60777-x
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