A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington’s disease patients

Huntington’s disease (HD) is a progressive neurodegenerative disease. Involuntary movements, cognitive impairment and psychiatric disturbance are the major clinical manifestations, and gradual atrophy and selective neuronal loss in the striatum and cerebral cortex are the pathologic hallmarks. HD is...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Liu, Peng, Smith, Benjamin R., Huang, Eric S., Mahesh, Abhishek, Vonsattel, Jean Paul G., Petersen, Ashley J., Gomez-Pastor, Rocio, Ashe, Karen H.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664763/
https://ncbi.nlm.nih.gov/pubmed/31358058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0764-9
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