Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells

Abnormal histone deacetylase (HDAC) expression is closely related to cancer development and progression. Many HDAC inhibitors have been widely used in cancer treatment; however, severe side effects often limit their clinical application. In this study, we attempted to identify natural compounds with...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Chen, Chi-Yuan, Chen, Chin-Chuan, Chuang, Wen-Yu, Leu, Yann-Lii, Ueng, Shir-Hwa, Hsueh, Chuen, Yeh, Chau-Ting, Wang, Tong-Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052045/
https://ncbi.nlm.nih.gov/pubmed/32158695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00216
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