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Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells

Abnormal histone deacetylase (HDAC) expression is closely related to cancer development and progression. Many HDAC inhibitors have been widely used in cancer treatment; however, severe side effects often limit their clinical application. In this study, we attempted to identify natural compounds with...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Chen, Chi-Yuan, Chen, Chin-Chuan, Chuang, Wen-Yu, Leu, Yann-Lii, Ueng, Shir-Hwa, Hsueh, Chuen, Yeh, Chau-Ting, Wang, Tong-Hong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052045/
https://ncbi.nlm.nih.gov/pubmed/32158695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00216
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