Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells

Abnormal histone deacetylase (HDAC) expression is closely related to cancer development and progression. Many HDAC inhibitors have been widely used in cancer treatment; however, severe side effects often limit their clinical application. In this study, we attempted to identify natural compounds with...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Chen, Chi-Yuan, Chen, Chin-Chuan, Chuang, Wen-Yu, Leu, Yann-Lii, Ueng, Shir-Hwa, Hsueh, Chuen, Yeh, Chau-Ting, Wang, Tong-Hong
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052045/
https://ncbi.nlm.nih.gov/pubmed/32158695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00216
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