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Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair

DNA repair systems are abnormally active in most hepatocellular carcinoma (HCC) cells due to accumulated mutations, resulting in elevated DNA repair capacity and resistance to chemotherapy and radiotherapy. Thus, targeting DNA repair mechanisms is a common treatment approach in HCC to sensitize canc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancers (Basel)
Egile Nagusiak: Chen, Chin-Chuan, Chen, Chi-Yuan, Wang, Shu-Huei, Yeh, Chau-Ting, Su, Shih-Chi, Ueng, Shir-Hwa, Chuang, Wen-Yu, Hsueh, Chuen, Wang, Tong-Hong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162454/
https://ncbi.nlm.nih.gov/pubmed/30201872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10090320
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