Conformational Response of N-Terminally Truncated Cytochrome P450 3A4 to Ligand Binding in Solution

Human cytochrome P450 3A4 (CYP3A4) is a membrane-associated monooxygenase that is responsible for metabolizing >50% of the pharmaceuticals in the current market, so studying its chemical mechanism and structural changes upon ligand binding will help provide deeper insights into drug metabolism an...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Biochemistry
Asıl Yazarlar: Chuo, Shih-Wei, Liou, Shu-Hao, Wang, Lee-Ping, Britt, R. David, Poulos, Thomas L., Sevrioukova, Irina F., Goodin, David B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048403/
https://ncbi.nlm.nih.gov/pubmed/31456404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00620
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller