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FAIM Opposes Aggregation of Mutant SOD1 That Typifies Some Forms of Familial Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative illness that is unremittingly fatal and for which no effective treatment exists. All forms of ALS are characterized by protein aggregation. In familial forms of ALS, specific and heritable aggregation-prone proteins have been ide...

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Bibliographische Detailangaben
Veröffentlicht in:Front Neurosci
Hauptverfasser: Kaku, Hiroaki, Ludlow, Alexander V., Gutknecht, Michael F., Rothstein, Thomas L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047752/
https://ncbi.nlm.nih.gov/pubmed/32153351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00110
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