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Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with an adult onset characterized by loss of both upper and lower motor neurons. In ~10% of cases, patients developed ALS with an apparent genetic linkage (familial ALS or fALS). Approximately 20% of fALS displays mutations in...

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Main Authors: Tan, Wenzhi, Pasinelli, Piera, Trotti, Davide
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074562/
https://ncbi.nlm.nih.gov/pubmed/24568860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.02.009
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