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Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with an adult onset characterized by loss of both upper and lower motor neurons. In ~10% of cases, patients developed ALS with an apparent genetic linkage (familial ALS or fALS). Approximately 20% of fALS displays mutations in...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074562/ https://ncbi.nlm.nih.gov/pubmed/24568860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.02.009 |
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