The protein C activator AB002 rapidly interrupts thrombus development in baboons

Although thrombin is a key enzyme in the coagulation cascade and is required for both normal hemostasis and pathologic thrombogenesis, it also participates in its own negative feedback via activation of protein C, which downregulates thrombin generation by enzymatically inactivating factors Va and V...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Blood
Hlavní autoři: Tucker, Erik I., Verbout, Norah G., Markway, Brandon D., Wallisch, Michael, Lorentz, Christina U., Hinds, Monica T., Shatzel, Joseph J., Pelc, Leslie A., Wood, David C., McCarty, Owen J. T., Di Cera, Enrico, Gruber, András
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2020
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046603/
https://ncbi.nlm.nih.gov/pubmed/31977000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002771
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky