The protein C activator AB002 rapidly interrupts thrombus development in baboons

Although thrombin is a key enzyme in the coagulation cascade and is required for both normal hemostasis and pathologic thrombogenesis, it also participates in its own negative feedback via activation of protein C, which downregulates thrombin generation by enzymatically inactivating factors Va and V...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Tucker, Erik I., Verbout, Norah G., Markway, Brandon D., Wallisch, Michael, Lorentz, Christina U., Hinds, Monica T., Shatzel, Joseph J., Pelc, Leslie A., Wood, David C., McCarty, Owen J. T., Di Cera, Enrico, Gruber, András
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046603/
https://ncbi.nlm.nih.gov/pubmed/31977000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002771
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados