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A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes

Trypanosomes have a trypanothione redox metabolism that provides the reducing equivalents for numerous essential processes, most being mediated by tryparedoxin (Tpx). While the biosynthesis and reduction of trypanothione are cytosolic, the molecular basis of the thiol redox homeostasis in the single...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Ebersoll, Samantha, Bogacz, Marta, Günter, Lina M, Dick, Tobias P, Krauth-Siegel, R Luise
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046469/
https://ncbi.nlm.nih.gov/pubmed/32003744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53227
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