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Mono- and Dithiol Glutaredoxins in the Trypanothione-Based Redox Metabolism of Pathogenic Trypanosomes

Significance: Glutaredoxins are ubiquitous small thiol proteins of the thioredoxin-fold superfamily. Two major groups are distinguished based on their active sites: the dithiol (2-C-Grxs) and the monothiol (1-C-Grxs) glutaredoxins with a CXXC and a CXXS active site motif, respectively. Glutaredoxins...

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Detalhes bibliográficos
Main Authors: Comini, Marcelo A., Krauth-Siegel, R. Luise, Bellanda, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739957/
https://ncbi.nlm.nih.gov/pubmed/22978520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4932
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