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Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

In trypanosomes, the thioredoxin-type protein TXN (tryparedoxin) is a multi-purpose oxidoreductase that is involved in the detoxification of hydroperoxides, the synthesis of DNA precursors and the replication of the kinetoplastid DNA. African trypanosomes possess two isoforms that are localized in t...

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Bibliografiske detaljer
Main Authors: Comini, Marcelo A., Krauth-Siegel, R. Luise, Flohé, Leopold
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783994/
https://ncbi.nlm.nih.gov/pubmed/17040206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061341
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