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Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

In trypanosomes, the thioredoxin-type protein TXN (tryparedoxin) is a multi-purpose oxidoreductase that is involved in the detoxification of hydroperoxides, the synthesis of DNA precursors and the replication of the kinetoplastid DNA. African trypanosomes possess two isoforms that are localized in t...

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Autors principals: Comini, Marcelo A., Krauth-Siegel, R. Luise, Flohé, Leopold
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783994/
https://ncbi.nlm.nih.gov/pubmed/17040206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061341
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