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Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

In trypanosomes, the thioredoxin-type protein TXN (tryparedoxin) is a multi-purpose oxidoreductase that is involved in the detoxification of hydroperoxides, the synthesis of DNA precursors and the replication of the kinetoplastid DNA. African trypanosomes possess two isoforms that are localized in t...

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Detalles Bibliográficos
Main Authors: Comini, Marcelo A., Krauth-Siegel, R. Luise, Flohé, Leopold
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783994/
https://ncbi.nlm.nih.gov/pubmed/17040206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061341
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