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A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes

Trypanosomes have a trypanothione redox metabolism that provides the reducing equivalents for numerous essential processes, most being mediated by tryparedoxin (Tpx). While the biosynthesis and reduction of trypanothione are cytosolic, the molecular basis of the thiol redox homeostasis in the single...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ebersoll, Samantha, Bogacz, Marta, Günter, Lina M, Dick, Tobias P, Krauth-Siegel, R Luise
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046469/
https://ncbi.nlm.nih.gov/pubmed/32003744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53227
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